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All identifications were manually validated and the proteins were selected and validated on basis of MOWSE scores, peptides matches, and % sequence coverage.
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In a first step, the inhibitor peptide structure is calculated on the basis of trNOE data; the trRDC data are then validated on the basis of the trNOE-derived structure using the program PALES.
Second, findings from the first analyses were replicated and validated on the basis of motives of compliance and non-compliance, and on the basis of behaviour in a tax experiment.
The performance of the PD score at predicting novel proteins was validated on the basis of 10-fold cross-validation test.
The assay was validated on the basis of the latest Food and Drug Administration FDAA) guideline for bioanalytical method validation [ 11], and was applied to a small set of samples obtained from healthy subjects, as a proof of concept.
A three-dimensional finite element model validated on the basis of experimental results is used.
It is validated on the basis of measured temperatures during fire tests.
The model was validated on the basis of real data collected from two clinical laboratories.
The MLP was trained and validated on the basis of the first 80 days (see Appendix 1).
Finite element models were developed and validated on the basis of the test results and very good agreement was achieved.
Here, an algorithm is presented which implements these calculations and is validated on the basis of two simple examples.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com