Exact(1)
Then we validated observed associations in an independent Spanish series, making this the largest sporadic MM susceptibility study in the Spanish population up to now.
Similar(59)
This is a novel method of validating observed associations involving genetics and observational epidemiologic data.
Access to supervisory-level data could be investigated as a means to validate observed model work group size findings.
We used proteomics, systems biology, and immunohistochemistry to explore protein expression in human endometrial tumours, to identify deregulated regulatory mechanisms, and to validate observed changes in protein expression using tissue microarrays.
The proposed model has been validated against observed data.
The bi-directional flow effects on free-flow walking speed, effective capacity and at-capacity walking speed are validated with observed data.
This could however not be validated against observed data as these do not exist.
To dispel any doubt we validated every observed mosaic CNVs by qPCR.
The relative hazards of different factors, including lymph node status, have previously been validated against observed mortality reduction in the trial in different age-groups including women aged 40 49 (Tabar et al, 1995a).
Ion Torrent sequencing validated previously observed Sanger results for KRAS mutations [ 13] and identified three additional KRAS variants that were not detectable by Sanger (likely due to low cellularity and restriction of the previous study to the amino acid 12/13 hotspot region. (Figs. 2 & 3; Additional file 1).
Second, the method can only validate previously observed associations; consequently, the inability to validate an association does not imply that it is false, it may simply be unknown (see the Discussion section).
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