Sentence examples for validated its role from inspiring English sources

After comparing the pTyr proteins that were differentially expressed during HCC cell metastasis, we selected FER, a nonreceptor tyrosine kinase, and validated its role in terms of both expression and function.

Furthermore, we found that silencing CDK6 expression using siRNA could inhibit proliferation and migration of osteosarcoma cells, whereas overexpressing CDK6 induced opposing effects, validating its role as an essential oncogene during osteosarcoma tumorigenesis.

Further investigations of the roles and mechanistic pathways of CD44 in tumor initiation and progression are required to validate its role in CSC maintenance and regulation, and provide further insight on its usefulness as a specific therapeutic target.

To independently validate its role, depletion of RILP by RNAi should have opposite consequence.

However, further investigations have to aim at validating its role in BNP pathogenesis.

However, the N39ID mutation completely abolished the ligase activity, validating its role in the peptide ligation.

Raffinose drastically decreased in content upon imbibition validating its role as transient C storage molecule as suggested earlier [ 37, 38].

Further studies to assess the functional consequences of this genetic variant, as well as to validate its role as a prognostic marker in this disease are certainly warranted.

In our study also, we found the preferential expression of OsROXY1 (OsGRX8) during stages of panicle development, which further validates its role in floral organ development.

However, further investigations of Hakai in in vitro and in vivo model systems would lead us to validate its role during tumorogensis.

Nevertheless, further investigations of Hakai in in vitro and in vivo model systems would lead us to validate its role during tumorigenesis.