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The T-RTS has been validated in many studies and is well able to distinguish between patients with good and poor prognoses [7].
The Rockall score and the Glasgow-Blatchford bleeding score, which have been validated in many studies [16, 17], were developed for early identification of high-risk patients needing intensive care and of low-risk patients who can be discharged early.
Introducing the concentric needle electrode opened a fruitful optimizing window to apply this sophisticated technique, which was validated in many studies (Ertas et al. 2000; Benatar et al. 2006; Sarrigiannis et al. 2006; Kouyoumdjian and Stalberg 2008; Stålberg and Sanders 2009).
The original HADS was translated into Chinese Mandarin and has been validated in many studies.
It has been validated in many studies and is one of the three most commonly used scale [ 21].
The scale has often been used in the assessment of mood in people of mixed ages, and it has been validated in many studies [ 11- 13].
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The quality measures used in this study, while validated in many other studies, may not have provided the most comprehensive description of quality for this sample.
The salmon custom array has been validated in many previous studies and for this particular study it had already been validated in liver tissue (Betancor et al., 2015).
The salmon microarray and laboratory procedures utilized in this study have been widely used and validated in many previous studies (e.g. Martinez-Rubio et al. [ 15, 19]; Morais et al. [ 20, 21]; Tacchi et al. [ 22]; Bicskei et al. [ 23]).
These findings were validated in many independent studies including participants with different genetic and socio-economic background, which indicates the reliability of this study.
Thus, we employ a simple approach that has been adopted and validated in many previous studies [8, 11].
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