Our approach was validated in a large independent case-control sequencing study.
This cellular interaction has been validated in a large number of experimental animal models where dys-regulation of the immune system plays a role.
The ideal prediction tool for infants born with CDH would be validated in a large population, generalizable, easily applied in a clinical setting and would clearly discriminate patients at the highest and lowest risk of death.
Although these results need to be validated in a large clinical trial, this pilot trial provides important data for clinical trial design of hypothermia treatment in neonatal hypoxic-ischemic injury.
This diagnostic management strategy was prospectively validated in a large Dutch cohort and has proved effective and safe [6].
OBJECTIVE: The use of cross-sectional area (CSA) measurements obtained from computed tomographic angiography (CTA) for the calculation of carotid artery stenosis has been suggested but not yet validated in a large population.
CONCLUSION A novel biomarker-based risk score for predicting stroke in AF was successfully developed and internally validated in a large cohort of patients with AF and further externally validated in an independent AF cohort.
These data will be further validated in a large prospective RA study presently being evaluated.
In a prevalence screen, some of the most interesting results were validated in a large cohort of ccRCC patients.
A prognostic gene expression signature has been proposed for survival in early-stage lung cancer [33] and was recently validated in a large, training-testing, multi-site, blinded study [34].
These findings should be validated in a large, prospective study.
