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Second the methodology developed here could be validated in a future study for a new rotor blade system to function well within the scoop.
Nevertheless, the results and findings of this study need to be validated in a future prospective study.
Third, and most importantly, because a longitudinal study was not performed to analyze the molecular changes during the development and progression of MM, the direct causal relationship between LINE-1 hypomethylation and genomic vulnerability remains to be validated in a future functional study.
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Therefore, the finding needs to be validated in a larger sample size in the future.
The 38 gene signature identified in our study, however, needs to be validated in a much larger cohort in the future to achieve its true potential as a prognostic panel in OTSCC.
However, because this study had no replication cohort and previous European studies have not reported the association for HLA-C amino-acid position 116, this association needs to be validated in an independent cohort in the future.
In fact, the evaluation of these more severely fatigued patients allowed us to identify biomarkers which will need to be validated in the future in a larger sample of patients.
We highlight the differential expression of p21 between the LMP without or with non-invasive implants compared to the more aggressive LMPs presenting invasive implants and suggest that this result be validated in the future on a larger set of LMPs with invasive implants.
Nevertheless, results presented here should be validated in the future with Cyr61 expressed by an eukaryotic expression system.
The reliability of this software for other types of repositioning surgery for maxillofacial fractures should be validated in the future.
These tests are important, since they may be validated in the future or be useful for studying factors influencing Pb bioaccessibility and bioavailability.
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