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Estimation of systolic pulmonary arterial pressure (SPAP) from the peak tricuspid regurgitant velocity is the most widely used echocardiographic measure of PH severity and has been validated in a broad range of clinical situations, although concerns about accuracy remain[5].
The instrument has been widely used and validated in a broad variety of populations [ 49].
It is widely translated and validated in a broad range of countries such as UK, The Netherlands, Belgium, Scotland and Norway [ 10- 15].
It is based on a combination of ICC and IF where specific markers for CTC, such as CK and EpCAM are linked to nuclear and leukocyte staining CSS has been validated in a broad clinical testing program.
The NPSI is the only tool validated in patients with neuropathic pain of central and peripheral origin and has a factorial design validated in a broad range neuropathic pain patients.
The Health Assessment Questionnaire (HAQ), developed originally at Stanford in the late 1970's to assess patients with rheumatoid arthritis, has been validated in a broad range of rheumatic and non-rheumatic disease populations [ 46, 47].
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These results were validated in a second replication cohort.
LIMITATIONS: The tool was validated in a small cohort.
These measures need to be validated in a larger sample.
These findings are being validated in an ongoing, prospective study.
The models validated in the broad frequency and temperature range allow designing heaters for microwave-assisted chemistry in a short time and with improved accuracy and enhanced efficiency.
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