Sentence examples for validated functions from inspiring English sources
Furthermore, a phylogenetic analysis of T. pseudonana and P. tricornutum Argonaute proteins revealed that they are only distantly related to canonical Argonaute proteins with experimentally validated functions, suggesting functional specialization [ 37].
The size of M. pneumoniae genome (Accession number: NC_016807.1) is relatively smaller as compared to other bacteria and contains 707 functional proteins, in which 204 are classified as hypothetical proteins (HPs) because of the unavailability of experimentally validated functions.
Our statistical model is based on sets of proteins with experimentally validated functions and numeric measures of function specificity and function similarity derived from the Gene Ontology.
With validated functions, some of the miRNAs may serve as candidates for the clinical diagnosis, prognosis and treatment of myeloid leukemias.
To help researchers better understand lncRNAs and their functions, the 'lncRNAdb' database focuses on collecting the validated functions of lncRNAs based on the published literature (9).
It is noted that the genes in the first class are genuine protein-coding with validated functions, while some ORFs in other classes may be random sequences that are falsely predicted as protein-coding genes.
The final dataset comprised 35 validated functioning PET tracers and 12 non-functioning tracers (Table 1).
One of these lineages (Lineage 1) comprises nearly all EXDO I proteins of validated function.
Among the three described lineages, AromaDeg is dedicated to Lineage 1, which comprises most of the EXDO I proteins of validated function.
The evidence associated with each gene includes any one of the following attributes: conservation of the gene, evidence of experimentally validated function or predicted molecular function, existing 3D structures or protein domains, protein purification status, EC numbers, and gene phenotype.
We found further that inhibiting NRP1 with a previously validated function-blocking antibody (Erskine et al., 2011) abrogated the ability of VEGF to promote GN11 cell survival (compare Fig. 3E with 3F; Fig. 3H; P<0.01).
