Sentence examples for validated function from inspiring English sources
One of these lineages (Lineage 1) comprises nearly all EXDO I proteins of validated function.
Among the three described lineages, AromaDeg is dedicated to Lineage 1, which comprises most of the EXDO I proteins of validated function.
The evidence associated with each gene includes any one of the following attributes: conservation of the gene, evidence of experimentally validated function or predicted molecular function, existing 3D structures or protein domains, protein purification status, EC numbers, and gene phenotype.
The cell-envelope set (termed 'set P') contained the sequences of 59 proteins that were homologous to proteins with an experimentally validated function specific for the periplasm, cell envelope, or extracellular environment.
Essentially, each query sequence that match a given protein family of AromaDeg is associated to a specific cluster of a given phylogenetic tree and further function annotation and/or substrate specificity may be inferred from the neighboring cluster members with experimentally validated function.
(a) +, experimentally validated function; °, in silico predicted function.
Furthermore, a phylogenetic analysis of T. pseudonana and P. tricornutum Argonaute proteins revealed that they are only distantly related to canonical Argonaute proteins with experimentally validated functions, suggesting functional specialization [ 37].
The final dataset comprised 35 validated functioning PET tracers and 12 non-functioning tracers (Table 1).
The size of M. pneumoniae genome (Accession number: NC_016807.1) is relatively smaller as compared to other bacteria and contains 707 functional proteins, in which 204 are classified as hypothetical proteins (HPs) because of the unavailability of experimentally validated functions.
Our statistical model is based on sets of proteins with experimentally validated functions and numeric measures of function specificity and function similarity derived from the Gene Ontology.
We found further that inhibiting NRP1 with a previously validated function-blocking antibody (Erskine et al., 2011) abrogated the ability of VEGF to promote GN11 cell survival (compare Fig. 3E with 3F; Fig. 3H; P<0.01).
