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The SNPs that were validated between the two parents were subjected to genotypes analysis in the DH population.
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Here, we validated findings between the two methods as well as between each method and manually curated clustering.
More recently, tiling oligonucleotide microarrays with 42 million probes, showed that an average of 1,098 CNVs comprising 0.78% of the human genome were validated between two individuals [ 49].
Since we started our study and selected promising targets before the publication of Dom's results, there is no overlap in the set of genes validated by qRT−PCR between the two studies.
Thus, we conclude that the mutations found to be unique in either the CSCs or bulk primary tumor cells were, when re-sequenced with ultra deep coverage, in fact validated as shared between the two compartments, or false positives in the original exome sequencing.
The newly developed dCAPS markers were validated by examining polymorphisms between the two parental lines C1184 and C1234.
Mate-pairs information is used judiciously during the merging process to further validate the connection between the two sequences.
7 Patients with vitiligo (n = 119) and psoriasis (n = 162) were included in a postal survey, and QoL was assessed by the Dermatology Life Quality Index (DLQI), in order to validate and compare differences between the two skin conditions.
To validate the comparison between the three tested introduced populations (Cameroon, Florida, New Caledonia) and the tested native populations (French Guiana), we investigated whether these introduced populations were genetically closer to three alternative sets of native populations from Brazil, Costa Rica or French Guiana.
We also validated the seven novel CNVs.
The availability of a reference genome allows the reconstruction procedure to be validated and highlights the diversity between the two genomes.
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