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The proposed tool represent a validated basis for pasta production process optimization and reverse engineering of die design.
Existing knowledge compiled as interactome networks can help to provide a validated basis in the search for biologically relevant driver genes.
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In order to validate this basis, we tested WiFiSim under different simulation conditions.
The database is then used to train and validate Radial Basis Function Artificial Neural Network (RBF ANN) input output "meta-models".
Finally, the database is used to train and validate Radial Basis Function Artificial Neural Network (RBF ANN) input output "meta-models".
The database is then used to train and validate Radial Basis Function Artificial Neural Network input output "meta-models".
The changes in binding energy associated with each variation were generally additive upon combining variations, validating the basis of the algorithm.
In a first step, the inhibitor peptide structure is calculated on the basis of trNOE data; the trRDC data are then validated on the basis of the trNOE-derived structure using the program PALES.
The performance of the PD score at predicting novel proteins was validated on the basis of 10-fold cross-validation test.
Second, findings from the first analyses were replicated and validated on the basis of motives of compliance and non-compliance, and on the basis of behaviour in a tax experiment.
The assay was validated on the basis of the latest Food and Drug Administration FDAA) guideline for bioanalytical method validation [ 11], and was applied to a small set of samples obtained from healthy subjects, as a proof of concept.
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