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Use of the von Willebrand factor concentrates, Humate-P and Wilate, were documented in this study only for patients with haemophilia A or B. CHR has previously been described and validated as representing the Canadian haemophilia population [ 8, 23, 25].
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However, the definition of an early stage of AS represents a methodological problem because there are no validated classification or diagnostic criteria [ 6].
Operationalization of validated constructs representing these project selection criteria presents a promising avenue for future research.
Damage is defined in this paper as a function of parameter changes of the verified and validated mathematical model representing the existing structure under investigation.
The validated fingerprints represented approximately 11.7-fold of the chickpea genome (Table 2).
The comparison between the original and cross-validated AUCs represents an internal validation measure of the fitting.
Unfortunately, time frames varied between the questionnaires, and as it was not possible to change this in the present validated form, it represents a limitation.
To test this, we split chrUr into 150 bp length "reads" and scanned this simulated "read" data using e-genotype probes created from all of our validated rhesus SNPs (3,271,622 probes, representing the reference position at all locations as well as the one or two non-reference validated alleles).
We identified 89 indels from our Clinical pipeline, of which 84 indels were covered in CapVal, and 83 validated as "SOMATIC".
The developed method was optimized and validated as per ICH guidelines.
Biological activity was validated as described [ 42].
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