Of those, we found 65 associations with GWAS traits and provide examples in which genes implicated by expression are functionally validated as being relevant for complex traits.
ECI has been validated as a relevant economic measure by showing its ability to predict future economic growth (see Hidalgo and Hausmann 2009), and explain international variations in income inequality (see Hartmann et al. 2017. This page includes rankings using the Economic Complexity Index (ECI).
Since neither average τ av nor defect-free bulk τ b positron lifetimes are changed under Ga additions, the two-state trapping model based on one preferential type of positron traps [22 26] can be validated as most relevant to the physically realistic channel of positron annihilation in these alloys.
Although identification of PTMs involved in the Wnt/β-catenin pathway and validation of their function are far from completion in fact a large number of PTMs are not all validated as physiological relevant, the concept that relaying Wnt signal requires dynamic changes in PTM states of the pathway components has been emerged.
After this step, five genes (TUBGCP4, NAT10, GTF3C1, BLOC1S1 and LRRC59) were validated as PA-1-relevant genes (Fig 3).
However, this did not work in all cases and additionally has not been validated as the most clinically relevant classification.
While existing literature established the relevance of WT1 for identifying future relapse, the WT1 test has not yet been validated as a relapse definition across relevant hematologic malignancies.
The developed approach to validate ERα36 as relevant prognostic marker is quite generic and can be applied to other genes as well as to a subset of genes G0.
To the best of our knowledge, BRCA1, SP1, TFE2, PO2F1 and ESR1 have not been experimentally validated as TFs of the identified OC relevant miRNAs.
Validated as the man said, "Please, Doctor.
