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We were also limited by the lack of ambulatory care sensitive conditions specifically validated as indicators of quality of care for Switzerland.
The modules of the HLQ used for the present study have been validated as part of the original validation study for the instrument reported in 1996.
This questionnaire was developed and validated as part of the International Quality of Life Assessment (IQOLA) project [ 12].
There is no cutoff level that would clearly improve the performance over the z-score of 3 originally validated as part of the laboratory-developed test.
Volumetric MRI measures of the MTL or hippocampus have been validated as markers of neuronal damage and can support the diagnosis of early AD [ 71].
These codes of ACSCs have been validated as markers of access to primary health care in the USA and Australia [ 7, 8].
The ECQ was developed and validated as part of the Edinburgh Artery Study [ 6] with the objective of improving the sensitivity of the WHO/Rose Claudication Questionnaire [ 15].
Cases are then confirmed and validated as part of the standard APCR validation processes.
Interleukin 6 or procalcitonin, two other inflammatory parameters, well described as markers of severity, have not been validated as markers of response to antibiotic therapy [ 26, 27].
Measures of 24hr urinary sugars have recently been validated as biomarkers of total and added sugars intake (17).
Some of these abnormally activated protein kinases will be validated as causal of disease, and therefore "targets".
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com