Sentence examples for validated active from inspiring English sources

DUD-E features 22,886 experimentally validated active compounds with an average number of 224 ligands per each protein target, and over 1,000,000 decoy molecules at an approximate ratio of 50 per 1 active compound.

Although we are not presenting results to challenge this idea, it is implicit in our approach that our randomly selected fragments or mini-modules (150 250 bp) from the genome are more likely non-functional by comparison to the experimentally validated active sequences.

The observation protocol included the validated Active Listening Observation Scale (ALOS-global), as well as three domains of positive communication, i.e. providing reassurance, a clear explanation, and a favourable prognosis.

In case there is poor compliance with the diaries, physical activity will also be measured with the validated Active Australia questionnaire [ 68- 70], administered by telephone the week after each assessment.

Total leisure-time PA reported for the previous week was calculated using the validated Active Australia questionnaire.

Exposure treatment in CBT which is a gradual exposure to the actual, feared stimulus in the patients mind and real life situations is the most empirically validated and active ingredient of CBT for anxiety disorders.

Our study unveiled for the first time the contribution of DR4 and DR5 to the apoptotic mechanisms elicited by oligomeric A β on cerebral microvascular ECs, providing insights into the signaling pathways triggered through their activation and validating their active role in A β-mediated apoptosis via RNA silencing.

Experimentally validated kinase actives were compiled from the ChEMBL compound database, hereafter referred to as the kinase binding database (KBD).

The model-flavone complex was used to validate the active site architecture, and structurally and functionally important residues were identified by subsequent characterization of the secondary structure.

The experimental tests designed to validate the active plasmonics concept, and to determine the energy requirements and response characteristics for plasmonic switching in gallium through a nanoscale light-induced structural transformation, is also elaborated in the chapter.

Based on the results of this review, it is recommended that more experimental work be carried out on real-world systems to experimentally validate the active heave compensation controllers being designed and simulated in literature.