Sentence examples for validated a significant decrease from inspiring English sources
We observed and validated a significant decrease of miR-1246 expressinn in B cells only from active SLE patients, but not in inactive SLE patients or healthy controls, which implicated a role of miR-1246 in active SLE and might be developed into a potential biomarker and a novel therapeutic target of active SLE.
Even more interesting were the findings on colon cancer that were further validated by measurement of metabolite levels; there was observed a significant decrease in citrate concentration in tumor samples as well as a down-regulation of the pyruvate dehydrogenase complex that controls the majority of glucose carbon flux into the TCA cycle.
The above observation is additionally validated by faster viral clearance in the upper respiratory tract and a significant decrease in MDA levels in MDA+0/V birds after vaccination.
A possible heteromerization between US28 and US27 could not be validated using the BRET approach, since the co-expression of US27-Rluc led to a significant decrease in US28-YFP expression levels (data not shown).
Salvado et al. validated that low Xist expression in patient derived xenografts is associated with drug response and a significant decrease of the ALDH+ breast CSC population after treatment with a histone deacetylase inhibitor (HDACi) abexinostat.
In our experience, a significant decrease in the number of differentially expressed genes is demonstrated when validating SAGE results using quantitative real-time polymerase chain reaction (qRT-PCR) with a custom-made, low-density array chip of 94 significant genes as indicated by SAGE (82).
To further validate this finding, we performed density measurements on spastin stainings of our neuronal cultures and confirmed a significant decrease in spastin protein level in SPG4 patients (49.7% decrease on average, P = 0.024, Fig. 3D).
They are expecting neither a significant increase nor a significant decrease in attendance this season.
After adjusting for other variables, there was also a significant decrease in deaths.
The long-term hope is a significant decrease in the city's reliance on fossil fuels.
By 1970, he had noticed, with alarm, a significant decrease in astronomical visibility.
