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The designer needs to understand when required tolerances are pushing the process to the limit and to specify where capability should be measured and validated.
When required, mice have been treated daily with 3 µg of control- or CXCL12-specific siRNA (sequence above), previously validated on cells.
Use when required.
Feed them when required.
Use metric measurements when required.
Customize the diagram when required.
Reapply as and when required.
Use as and when required.
Report to the Unemployment Insurance Claims Office when required.
When legally required mutagenicity testing of chemicals is undertaken, the important genetic end point of aneuploidy is not included because validated test methods are lacking.
Simulations are validated when available.
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