Sentence examples for validate this up-regulation from inspiring English sources

However, qPCR did not validate this up-regulation.

Strikingly, this up-regulation is not transcriptional.

The reason for this up-regulation is not yet known.

This up-regulation is concordant with the up-regulation of the previously described defense loci.

This up-regulation was significantly lower in MMP13−/− mice.

The mechanism for this up-regulation is unknown.

This up-regulation has different consequences on gene expression.

We have used both western blot and immunohistochemistry analyses to validate the up-regulation of Ngn3 transcripts in Hnf6 Tg pancreata (Figure 5).

Here, although no gene sets fell below our false discovery cut-off of 0.05, we did observe borderline up-regulation of gene sets in "mRNA processing reactome" and in the "Regulation of Mitosis" and we were able to validate the up-regulation of several of the leading edge transcripts by qRT-PCR (Figure 5G,H).

Therefore, to validate the up-regulation of the nitrogenase genes, an RT-qPCR analysis was carried out for the nifH gene, which encodes a nitrogenase reductase subunit.

To validate the up-regulation observed in MB gene expression profiles, JAG1 mRNA levels were quantified in an additional independent cohort of 47 MB primary samples collected at the Children's Hospital of Zurich.