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The remaining patients (n=222) were assigned as the validation subgroup to validate the prognostic value of TrkB expression status using these cut-off values.
An independent cohort of 460 patient specimens obtained between 1992 and 2013 in the TCGA database (http://tcga-data.nci.nih.gov/tcga/) was used as an external validation cohort to validate the prognostic value of PA28γ in patients with HNSCC (Table S1).
The cut-off value of this training cohort for AFU was then applied to an independent prospective cohort at the second stage of the study to validate the prognostic value of AFU (the validation cohort) on the RFS and OS after surgery.
The aim of the present study was to similarly validate the prognostic value of FT-AT in patients infected with HBV and to use these non-invasive markers for a simpler definition of HBV inactive carrier status.
Further studies are needed to validate the prognostic value of SMI detected by ambulatory ECG.
Further studies are warranted to validate the prognostic value of OPN in independent cohorts of colorectal cancer patients.
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Large prospective studies are needed to validate the prognostic values of CTCs with multiple time points in homogeneous GC patients.
We were able to validate the prognostic values of MSKCC factors and evaluate the role of new markers of systemic inflammation using high quality randomised trial data.
In this study, we validated the prognostic value of the staging system in a patient cohort undergoing hepatic resection with longterm followup.
We validated the prognostic value of MELD-Na and UKELD in ALF.
We also validated the prognostic value of the known but understudied molecule IGFBP2 in a secondary CRC dataset.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com