"That's important input for us — and the recommendations [we provide to our clients] are, broadly speaking, two sorts: ones that are like things that they are already tracking, and that's easy to validate because it's things that may have slipped through the cracks.
None of the serological tests, however, have been validated because it is very difficult to isolate N. caninum from asymptomatic hosts [ 1].
Unfortunately, as MRI2 is a relatively new concept its prognostic value has not been validated, especially because it is done only in a subset of patients and with different protocols.
It can't be validated because it's not the story of the white, Western majority.
Nevertheless, we chose to validate the BAASIS® because it is concise, it seemed to comprise the relevant questions, and from the three proposed instruments, it is the only one already in use for transplant patients in other countries [ 15].
Further studies might be needed to validate this relation because it is difficult for the authors to figure out the underlying mechanism associated with accommodation and blinking rate with 3D displays in this study.
Neuroimaging researchers use simulation studies to validate their statistical methods because it is acknowledged that this is the most feasible way to know the ground truth of the data.
However, we are not aware of in vitro observations that can be used to validate this SMS behavior, possibly because it is challenging (and expensive) to maintain large EMT6 spheroids in culture for 50 days or more (although Chignola et al. have maintained Rat 9L spheroids to 70 days [ 16]).
The method was initially designed and validated using normal kidney tissue because it is a readily available source of tissue, and because we disposed of published data regarding the segmental expression of thousands of genes in such tissue.
We therefore chose the EUROPEP-instrument because it is validated, used in many surveys and exists in the languages of all participants [ 27].
