Sentence examples for valid reporter from inspiring English sources

Despite the lack of solid evidence to associate a possibly valid reporter to a gene, for studies relating expression levels to genomic positions (e.g., reference [ 10]), it makes sense to include these reporters.

A fully valid reporter must have MegaBLAST alignments to the RefSeq RNA transcripts of exactly one gene in Entrez Gene, and at least one of those alignments must be high-quality as defined in Methods.

An example of a fully valid reporter that is not annotated with a gene symbol or the identifier of a transcript is reporter ID 27386, which aligns perfectly to transcripts of the gene RPP14 (GeneID: 11102).

It is safe to use the 25505 fully valid reporters.

Excluding the 27364 (64%) fully valid and Refseq RNA valid reporters leaves 15319 (36%) reporters.

The lack of a gene symbol in the annotation file eliminates 6089 of the 9964 reporters we consider invalid, and also eliminates 799 of the 25505 fully valid reporters, 148 of the 1859 Refseq RNA valid reporters, 1273 of the 2187 other gene valid reporters, and 2470 of 3168 possibly valid reporters.

The sum of the four rightmost columns gives the 2565 RNA valid reporters in Table 1.

Fully valid reporters are permitted to have additional alignments to their corresponding gene, to the reverse complement of a different gene, to intergenic regions, or to untranscribed pseudogenes.

Fully valid reporters can be associated with the transcripts of a single gene and with chromosomal locations that lie within the same gene.

Other gene valid reporters can be placed on the chromosome within the location of a single gene, but the reporter either lies in an intron of that gene or in a transcript not yet in RefSeq.

Possibly valid reporters can be placed at a unique location on the human reference assembly, but this location is not the position of a gene currently in Entrez Gene.