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The valid question of whether any streaming music can turn a profit was also off the agenda.
Frequently, encouraging signals of potential efficacy for novel agents in early phase clinical trials have been followed by disappointing failures in larger phase III trials, raising the valid question of how drug development can be optimized for patients with pancreatic adenocarcinoma and biliary tract malignancies.
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"When will we see the elephants?" Not too long ago that was a valid question on the outskirts of the city, but nowadays you get ribbon development and traffic.
Yet he is right to point out that valid questions of sovereignty lie at the heart of Europe.
And yet, for all his admirers, there are plenty who ask valid questions of his record.
It's a valid question to wonder whether some of those publishers who've partnered with Flipboard felt comfortable doing so because it was an app – a separate digital space on tablets and smartphones – rather than another website.
Though he concedes that "it's clearly a valid question to think through the impact of the BBC having 55 per cent [audience] share", Davie says commercial radio has nothing to fear from his ambition, if it is willing to work with him.
The media has plenty of other valid questions to be asking Republican (and Democratic, for that matter) candidates on the issue of foreign policy, but so far they haven't actually been asking any such questions (more on this later in the talking points segment of our program).
Most lecturers have probably experienced the difficulties of constructing valid questions for written exams.
And all of those are valid questions for a team that has struggled for the last two months.
Glenn Hubbard, the economic adviser who helped design Bush's 2003 tax cuts, is nettled by a perfectly valid question about conflict of interest and suddenly snaps: "You have one more question," he tells the interviewer with a sneer, "... give it your best shot".
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com