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There are counterproductive hangups in the western world that all valid interaction with North Korea should involve some kind of human rights lecturing – I don't believe in that".
As long as there is no direct conflict between the SRPreCondition and SRPostCondition, a link can be formed (for certain valid interaction intentions).
However, the low level of protein that provides only a single identified peptide makes a distinction between a valid interaction and a contaminating protein more difficult.
Requiring at least two peptides of a protein to be identified as a valid interaction reduces the chances of recovering a single peptide from a low level contaminant.
Each Pubmed ID was associated with unique and valid interaction types and experimental methods as provided by the source databases.
In cases where a valid interaction detection method was not specified by the source database, the interactions are assigned to 'unknown' method and consequently given a poor score.
Similar(53)
Sequencing Hi-C libraries from untreated cells or those treated with TGF-β (for 8 or 24 h) resulted in 89 106 M valid interactions per time point (Supplementary Table 2), which allowed us to generate chromosome-wide interaction maps at 100 and 40 Kb resolution for A/B (activated/repressed) compartments and TAD analyses, respectively.
Single peptide identifications can be from valid interactions and are therefore still useful in a database, but are included only in the supplemental tables and would require further experimental verification of the possible interaction.
The third protein (Os02g33450) appears in both data sets more than once making any conclusions more difficult about whether these are valid interactions or the result of a "sticky" protein in both systems.
Each reference was verified manually to ensure the citation of valid interactions.
By default, interactions with a medium score as defined by STRING (400 or greater) constitute valid interactions.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com