EBM does not clearly address the role of basic science in medical discovery, except to indicate that, in most circumstances of relevance to individual patient care, basic science alone does not provide valid and practical guidance.
Despite of known informatics constrains, such as, model overfitting and limitations in the employed functional assays the results suggest that comparative analyses for defining conserved repressor elements is a valid approach providing efficient guidance for the experimental validation.
I acknowledge that there could be a valid purpose in issuing guidance on this topic – social media is a fast moving environment and it is easy to slip up, or for the inexperienced or thoughtless to create an unintended bad impression or disastrous chain reaction by messing with the magick of the interwebs.
A valid source of information and guidance is unnecessarily lost.
We assessed all aspects of prescriptions that make them legal and valid, in accordance with national guidance [ 3].
However the IOM guidelines have been deemed safe and there is a valid argument for having such guidance as a reference, particularly in an attempt to minimise excessive weight gain, and minimise the risk of post-partum weight retention [ 31].
We found that the self-reported questionnaire of medication use for hypertension, diabetes and dyslipidaemia that is conducted as part of the annual health check-up in Japan's health guidance programme is a valid measure of true medication use.
The instrument was developed to meet regulatory guidance, with initial validation evidence suggesting that the CD-PRO/SS scores are reliable, valid, and ready for use and further testing in clinical trials.
Tracy knows that not just any book will read as authentic psychic guidance, say, or as offering valid "energy secrets".
Eisenberg-Michalowski explains that many attorneys will take valid discrimination cases, but neglect to provide guidance for their deaf client.
