Recently our group conducted a clinical trial which provided evidence that sham laser acupuncture can be used as a valid control for laser acupuncture trials.
WKY serve as a valid control for SHR since their behavioural characteristics are similar to those of other rat strains [ 47].
Certain albumin batches possess well-documented proinflammatory actions (for example, activating E-selectin, ICAM-1, vascular cell adhesion molecule 1), which seriously question the relevance of human albumin as a valid control for studies concerning inflammation [ 43].
Regarding the cardiac arrest syndrome, the systemic inflammatory response and secondary effects of most organ systems makes it even more difficult to find a valid control for RNA load.
During MGMT amplification, five DNAs (cases n°7, 19, 26, 37, 38) showed uncertain or failed controls of conversion but valid controls of conversion for LINE-1 and MLH1 markers.
For cryo-preserved tissues, DNA n° 21 displayed a valid control of conversion for LINE-1 and MGMT markers and an uncertain or failed control of conversion when amplified for the MLH1 marker.
The main advantage of this method is that only operation and design data about the plant are needed to obtain a valid control strategy for the process.
These results suggest that GHB-C rats may constitute a valid control line for GHB-S and GHB-R rats, representing the "general population" from which GHB-S and GHB-R rats were derived.
However, the accuracy of this technique heavily relies on the use of multiple valid control genes for normalization.
However these trials were not initially designed to evaluate the efficacy of maintenance with the targeted agent, and there is no valid control arm for the maintenance part of the trials.
