The proposed model, termed the elastic plastic hybrid adhesion model, is valid for the entire adhesion parameter range and also for elastic plastic contacts.
A limitation of the IDMT-based models is that they are only valid for application cases with low adhesion parameter values.
A more valid estimate of the disease burden of adhesions will increase the awareness of this complication, which can be used in counselling and clinical practice.
Circulating levels of adhesion molecules have been regarded as a valid index of endothelial activation.
These results are very important for all anti-adhesion agents, as they show that adhesion reduction using an anti-adhesion agent is a valid endpoint.
This rounded morphology and the distribution of focal adhesions observed in cells depleted of Rac3 is also valid for MCF-7 cells, but it was less striking, as many cells became round but some of them remained elongated.
Certain albumin batches possess well-documented proinflammatory actions (for example, activating E-selectin, ICAM-1, vascular cell adhesion molecule 1), which seriously question the relevance of human albumin as a valid control for studies concerning inflammation [ 43].
Although this model is artificial in many aspects, flow chamber experiments have proven valid for studying cell interactions in a number of studies including direct comparison with leukocyte adhesion in animals [ 26, 46].
In this research, a contacting rough surface adhesion model was developed by combining an extended Maugis Dugdale (EMD) model (which is only valid for elastic contacts) with an IDMT-based elastic plastic adhesion model.
The concern over the relationship between soluble vascular cell adhesion molecule-1 (sVCAM-1), lipid parameters, and the development of macroalbuminuria is quite valid.
