Given the fact that not all age-groups were eligible to receive the vaccine, impact of vaccination on meningococcal carriage would be beneficial for the whole population by reducing transmission.
These data can be used to evaluate current HPV vaccination program in the future, including vaccine impact on HR genotype prevalence.
Plans for monitoring vaccine impact involve pre- and post-vaccination assessment of cervical HPV DNA in the general population and in high grade abnormalities.
15 We did probabilistic sensitivity analysis by Latin hypercube sampling from the joint distribution of the economic parameters together with 100 outcome scenarios from the vaccine impact model that best fits pre-vaccination epidemiological data.
The following information was collected: year of vaccine introduction into the public and private sectors, vaccine formulation used, timing of annual vaccination campaigns, purchase of vaccine through the RF, criteria used for vaccine introduction, the status of vaccine impact evaluations, population risk groups targeted for vaccination, and the associated coverage rates.
For an estimate of Cervarix® vaccine impact it is important to ascertain the effect of the vaccination programme on the whole population, with particular focus on the age group where these changes will be observed first.
In order to estimate vaccine impact it is important to ascertain the effect of the vaccination programme on the whole population, with particular focus on the age group where these changes will be initially observed.
Immunization program delivery strategies that enable high vaccine coverage, particularly in inaccessible and remote areas, are critical to achieving optimal vaccine impact.
Optimal sampling of carriage could lead to improvements in downstream analysis and the evaluation of pneumococcal vaccine impact and extrapolation to pneumococcal disease control therefore further in depth comparisons would be of value.
To assess the potential effect of behavioral disinhibition on the trajectory of Brazil's epidemic in the presence of an AIDS vaccine, vaccine impact scenarios were explored in which a 50% decline in condom use was considered either immediately after vaccine introduction or more gradually over time.
