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My advice to aging parents: Make your health care wishes known to your children with the utmost specificity.
To target the Phox2b-expressing RTN neurons with utmost specificity, we exploited the fact that the majority of them belongs to the small set of neurons that co-express the Phox2b and Atoh1 transcription factors in the embryo (Dubreuil et al., 2009; Rose et al., 2009b).
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To ensure utmost biological relevance, tissue specificity filtering was adopted.
But I realized, as specificity was of utmost importance, the colloquial would have to do.
It is of utmost importance to validate the specificity of antibodies generated against proteins, which have high homology with other members of the same family.
In population-based screening, specificity is of utmost importance, as it basically determines the costs of the programme and the amount of unwanted adverse effects (anxiety, repetitive and confirmatory tests, as well as unnecessary colposcopy referrals and treatments) in the generally healthy population.
Lesion characterisation on the CT portion of the PET/CT study is therefore of utmost importance as it increases the specificity of PET/CT reporting [10].
Therefore, it has also been acknowledged for decades now in medical education, that as human performances are very much content or case specific, a principle known as the 'content specificity' of performances, it is of utmost importance to sample performance across a sufficient number of cases or patients or subjects for reliable performance scores [ 15].
The region between helix F and helix G comprises part of the substrate channel and is closely related to the structure variability under the inducement of substrate [18], [19] and substrate specificity [20], which is of utmost important to the function of the CYP3 family.
Therefore, understanding the determinants of the substrate specificity of PCSKs enzymes is of utmost importance.
To ensure utmost biological relevance for the 1,015 interactions, tissue specificity filtering was adopted (see Methods section).
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com