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Primers were selected within regions of unique sequence utilizing publicly available sequence databases [ 16- 24].
Wang's laboratory provides useful information for human genetic studies utilizing protein sequence information [ 4].
The second approach to cluster non-redundant sequences utilized sequence matches to the HomoloGene database of groups of homologous sequences from sequenced genomes [ 54].
The feasibility of utilizing sequence features that can be viewed as evolutionary changes in the sequence occurring in the operating taxonomic units has received considerable interest.
Oligonucleotides for CSGE and sequencing (Table 1) were designed using Primer3 software [ 26], utilizing sequence information obtained from public databases.
We report here on the application of a massively parallel sequencing approach utilizing sequencing-by-synthesis [ 10] as an efficient approach to generate ESTs.
Yet in Saturday's second inning he was punished for utilizing a familiar sequence.
These results in their entirety demonstrate the feasibility of utilizing sequence information for the prediction of interaction specificity, and represent a significant step forward towards a system-level understanding of entire signaling networks in bacterial organisms.
A variety of population genetics approaches exist to quantify adaptive evolution utilizing sequence divergence between species.
In this work, we propose utilizing sequence neutrality as an SVM feature to classify potential structured RNAs.
Utilizing sequence data from 458 individuals with hypertriglyceridemia and 333 controls with normal plasma triglyceride levels, we investigated these issues using GCKR, encoding glucokinase regulatory protein.
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