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Utilizing the best model, we calculated the length at which the probability of maturing was 50% (L P50 ) to illustrate the midpoint of the PMRN: (11) Temporal variation in L P50 values was evaluated by assessing the significance of the coefficients for the cohort terms in the GLMs and by regressing the predicted L P50 values against cohort.
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The IC50 was determined using XLfit version 4.2.1, utilizing the best fit model for each data set.
To evaluate the rate of molecular evolution at each locus, standard likelihood ratio tests were performed on individual loci as in [21], utilizing the best-fit model and the same model constrained by clock assumptions.
In all cases phylogenetic trees were estimated using the ML method implemented by the PAUP* 4.0 package [73] and utilizing the best-fit model of nucleotide substitution as determined by MODELTEST [74], which in each case was the most general time-reversible GTR+Γ4+I model (full parameter values available from the authors on request).
"We end up utilizing the best available observations at any given time," Schwadron said.
The programs PROTTEST [ 84] and ModelGenerator [ 85] were utilized to determine the best model for each ML analysis.
The ProtTest 2.4 Server was utilized to determine the best model of protein evolution for phylogenetic reconstruction [ 33].
A second model, designated as the baseline case, utilizes the best available literature model to obtain heat transfer results for comparison with those from the reality model.
Finally, the best model is utilized to model FC in an Iranian resting-state fMRI data.
The best model is probably the aged monkey (Price et al. 1994), however, because of the time and cost involved in utilizing this model, most studies have been focused on developing murine models.
The best model identified by 3d QSAR pharmacophore search served as suitable modes of superimposition for subsequent CoMFA utilizing compounds (D1-30), as training set.
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