Exact(2)
However, other studies also utilizing murine models of melanoma have found positive correlations between increased GM-CSF levels and growth of lesions 72.
Interestingly, recently published data by our group utilizing murine models of infection and trauma do not completely support this severely exacerbated gene expression pattern in mice of advanced age, although restoration of genomic homeostasis is certainly delayed [ 10, 11].
Similar(58)
Similarly, conflicting results have been reported utilizing murine models.
28 The beneficial effects of bortezomib on bone disease in MM have also been demonstrated in vivo through studies utilizing murine models.
To adequately evaluate the mutual interaction of breast cancer cells and inflammatory cells including MDSCs, we utilized murine models in which breast cancer cells were orthotopically grafted into immunocompetent syngeneic mice [ 22].
Potentially different behavior of hemopexin in mice and humans may be important to consider when utilizing murine models to represent acute human inflammatory diseases in which heme plays a role.
These studies utilizing three murine models of different types of B-cell lymphoma collectively demonstrate in vivo activity of AR-42.
HFHC diets have been extensively utilized for murine models of obesity, diabetes, and fatty liver.
Because tracking these events in patients in a controlled manner is not feasible, we utilized a murine model of DC vaccination to better understand the events following DC injection.
To address these questions, we utilized a murine model of susceptibility to allergen-induced airway hyperresponsiveness (AHR) wherein intratracheal administration of house dust mite (HDM) induces the development of AHR in susceptible A/J animals, but has little impact on AHR in resistant C3H mice.
To test this, we utilized a murine model of T. cruzi infection.
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