In this study, we utilized comparative approaches based on a phylogenetic framework to characterize lineage-specific genes in the parasitic protozoan phylum Apicomplexa.
However, to utilize comparative approaches with completely sequenced and assembled tree reference genomes as a means to identify potential candidate genes in marked intervals of less well sequence characterized species, we need to access the degree of preservation among tree genomes at a high resolution level, e.g. within 1 centiMorgan (cM) windows.
In the absence of complete genome sequences and given the relatively high gene order conservation (collinearity) observed in the grass genomes, genomics studies in the Triticeae have utilized comparative genomics approaches with other grass genomes.
We utilized comparative and integrative approaches for interpreting transcriptomics and proteomics results into hypothetical mechanisms of action underlying observed effects of 2A-DNT exposure in Northern bobwhite.
The Robetta protein structure prediction server [29], which utilizes comparative as well as ab initio approaches, was used to create a structural model of the complete G8R protein using the yeast PCNA crystal structure (PDB 1PLQ) as a template.
Present investigation utilized comparative genomics, transcriptome profiling and whole genome re-sequencing approaches and provided a systematic description of soybean SWEET genes and identified putative candidates with probable roles in the reproductive tissue development.
In such cases, docking studies utilize comparative models.
We utilized the constant comparative approach in our analysis [ 35] consistent with Grounded Theory [ 36].
By taking a comparative approach utilizing both sequence information and the chromosomal locations of the gene family members (relative to their neighboring genes) we propose that the expansion of the opioid peptide gene family is a result of the two whole genome duplications together with one local duplication, see Fig. 7A.
While there may be species- and brain region-specific effects of fluoxetine, uncovering potential universal mechanisms of action of fluoxetine will need to utilize a more comprehensive comparative approach.
[ 36] in order to analyze their target operons, and reconstruct and functionally annotate the respective regulons by utilizing a comparative genomics approach (see Methods).
