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Early epigenetic attempts have been limited to approaches utilizing candidate genes or cell-culture-based discovery, with validation using well-characterized pathology specimens from homogeneous cohorts.
In this study, numerical calculations have been conducted to compare the required heat transfer areas of the IFVs utilizing candidate refrigerants of propylene, propane, isobutane, butane and dimethylether and operating under various saturation temperatures.
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A plausible non-invasive approach to study adaptive variation in threatened species is to utilize candidate genes for interesting phenotypes that are known a priori or from mapping experiments in related model species [1].
In Figure 1 figure supplement 2B, we have further utilized candidate kinase activity profiles in a case study to confirm fidelity of our interpretation.
Mammalian DNA ligases, PCNA loader (RFC), MutS-α, MutL-α are among the likely ATP utilizing candidates involved in the reaction.
Utilizing a candidate gene association approach, we genotyped 21 SNPs within and around MECP2 in SLE patients and controls.
Utilizing a candidate gene approach, we first identified significant association with MECP2 SNPs and SLE in a cohort of Korean SLE patients and controls.
Stepwise linear regression analyses, utilizing six candidate anthropomorphic measures as potential independent predictors, were performed to predict HOMA-IR.
An important task for a genetic epidemiologist utilizing a candidate gene approach is the selection of appropriate genes and SNPs for testing the disease association.
It is possible that our findings are crucial for revealing the potentialities of utilizing these candidate BdbZIPs to improve productivity of grass plants and cereal crops.
In a population of HIV-infected malnourished adults in Zambia, the minimum proportional reductions in mortality and loss to follow-up necessary for a combined nutrition support and ART treatment program to maintain cost-effectiveness parity with ART alone appear to be reasonable endpoints for prospective studies utilizing several candidate supplements.
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