Design: Statewide, population-based, pragmatic study that utilizes a longitudinal survey of people hospitalized with TBI in South Carolina.
Our study is innovative given the scope and diversity of measures utilized within a longitudinal study design, allowing us to document any functional and psychosocial changes over time.
These limitations limit us from making any causal conclusion, and these limitations can be improved in future studies by utilizing a longitudinal design with multiple data sources.
Utilizing a longitudinal cross-sectional repeated measures design, One hundred sixteen healthy active-duty military personnel (80% male) were studied before, during, and 24 h after the course.
Given the extent to which spasticity is present in stroke survivors and the paucity of data examining the impact of spasticity on stroke survivors' HRQoL, we utilized a longitudinal cohort study of stroke survivors to examine the impact of spasticity on HRQoL.
Our study, utilizing the rich data from a longitudinal study, including recorded consultations and interviews, adds to this literature, demonstrating how review consultations are focused around the demands of QOF, to the detriment of patients' concerns and expectations.
Additionally, Quintanilha et al [ 16] utilized US B-mode inaging in a longitudinal study to follow-up the effects of bone marrow stem cell therapy in rats submitted to liver injury, while Ju et al [ 17] prospectively tracked stem cells labeled with super paramagnetic particles transplanted intrasplenically in cirrhotic rats by MRI.
In this project we followed a longitudinal study setup utilizing transcriptomics data from two of our recent studies [ 8, 14].
Taken together, they utilize the full information available in a longitudinal study on the temporal dimension of chronic disease progression.
