Sentence examples for utilizing a functional assay from inspiring English sources

A total of 1,382 compounds with positive allosteric modulation (PAM) of the mGluR5 glutamate response were identified through high-throughput screening (HTS) of a diverse library of 144,475 substances utilizing a functional assay measuring receptor-induced intracellular release of calcium.

The T-cell-dependent antibody response (TDAR) is a functional assay widely utilized in the chemical and pharmaceutical industries to assess the ability of a test system to mount an antibody response (IgM and/or IgG) against a T-cell-dependent antigen.

Fig. 2 Quantitative MUC assay for six fosmid clones that were identified using a functional assay with the CMB substrate.

In addition, while it is possible that different assay types (e.g. a binding assay instead of a functional assay) may influence the conclusions drawn here, we believe this is unlikely due to the fact that the dataset did not consist of agonists (in which case binding assays and functional assays may not correlate well in every case), but only of antagonists.

For enzymes, this involves a functional assay.

To assess the validity of a functional assay, one must consider how closely the functional assay reflects the biological environment.

Here, we utilized a functional siRNA kinomic screen to identify factors involved in SMC-resistance.

Thus utilizing a combination of functional assays and genomics, we identified fakA, a known virulence factor regulator and a fatty acid kinase, as an important negative regulator of biofilm formation in S. aureus USA300.

Novel SNP alleles were analyzed for potential differential splicing in vitro utilizing a splicing assay.

Viable cells were quantified in 12-well dishes utilizing a fluorimetric assay (CellTiter-Blue Cell Viability Assay, Promega, Mannheim, Germany).

Individual liver and spleen sections were screened for apoptosis utilizing a TUNEL assay.