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FastSNP utilizes information available from another online program PolyPhen (http://www.bork.embl-heidelberg.de/PolyPhen/) to predict whether any SNPs causing missense mutations will also cause a non-conservative change in protein structure [ 15].
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Thus, the only validation of the predicted SDRs utilized information available from homologous GPCRs: In a homology model based on a high-resolution X-ray crystallographic structure of rhodopsin [40], the 22 putative SDRs occupy the region corresponding to the retinal binding site.
For the whole range of topology connectivity, performance of greedy and local versions of the proposed gradient ascent method matches performance of the centralized version that utilizes all information available in the network.
By limiting our analysis to the last SBT preceding extubation, we have utilized the information available to clinicians making the decision to extubate; however there may be information utilized by physicians in following SBT results from day to day, which were not captured in this study.
Schema-level matchers utilize the information available in input schemas to find matches between schema elements.
The key idea in the proposed system is to utilize contextual information available in a musical scene.
Different methods utilize different information available in experiments which can be in the form of time series, drug perturbation experiments, gene knockouts, and combinations of experimental conditions.
Efficiency estimates from each method were very similar and suggest that human observers are not very efficient at utilizing the information available to discriminate videos of human action.
We performed comprehensive simulation studies to compare the performance of our new method, PAGAN, to that of alternative methods for alignment extension and to test how the different approaches utilize the information available in related sequences.
After the first round of classification, additional MapMan bins were manually assigned, if needed, via text search for GO, KEGG, COG, and MIPS ontology annotation for each probe set utilizing the information available at the GeneBins database [ 60].
Whereas the pair-wise comparisons carried out in hypothesis-testing procedures cannot utilize the information available from other dose groups, the strength of regression methods lies in the fact that the statistical power contained in the entirety of experimental observations is accessible for low-effect dose estimations.
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