To test this prediction, we first utilized computational methods to predict conserved fRNA secondary structures within multiple species alignments of Saccharomyces sensu strico genomes.
Systematic screens for sRNAs have focused mostly on intergenic regions and utilized computational methods [ 5– 10], shotgun cloning strategies [ 11, 12] and high-density oligonucleotide probe arrays [ 13– 15].
We therefore utilized computational methods to test the hypothesis that some of the genes within this large up-regulated cluster are co-ordinately regulated by common transcriptional mechanisms.
As these mutations were not reported in earlier studies, we further characterized the effect of these mutations on the protein function and stability utilizing computational methods such as SIFT, Polyphen, and MD simulations.
CAMM also utilizes computational linguistics methods for comparison of clinical annotations from multiple datasets.
The framework utilizes novel computational methods which enable evaluating the model fragility with respect to quantitative performance measures and parameters such as reaction rate constants and initial conditions.
This study utilizes computational topology optimization methods for the systematic design of optimal multifunctional silicon anode structures for lithium-ion batteries.
Series Editors: Bertino, E., Cioffi-Revilla, C., Foster, J., Gilbert, N., Golbeck, J., Gonçalves, B., Kitts, J.A., Liebovitch, L.S., Matei, S.A., Nijholt, A., Nowak, A., Savit, R., Squazzoni, F., Vinciarelli, A. A series of authored and edited monographs that utilize quantitative and computational methods to model, analyze and interpret large-scale social phenomena.
Dr. Lee has over 15 years of experience in industry and academia in public health operations research, which involves developing and utilizing mathematical and computational methods, models, and tools to help stakeholders better understand decision making, processes, and systems.
In this work, we have utilized spectroscopic and computational methods to investigate the as-isolated forms of CDO, as well as Cys-bound Fe(III CDO, both in the absence and presence of azide (a mimic of superoxide).
Physical characteristics of the FAC are described and individual correction factors are discussed focusing on computational methods utilized in their estimation.
