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However, cells are nature's nanotechnology engineering at the scale of atoms and molecules, and it might be better to envision a microchip that utilizes a single cell as an experimentation platform.
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To achieve the goal of profiling small RNAs and mRNAs from the same single cells, we utilized a half-cell genomics approach in which a single cell was lysed and the lysate was split evenly into two half-cell fractions, with each fraction subjected to either miRNA or mRNA transcriptome sequencing (Fig. 1a c).
In order to visualize a single cell layer, an optical slice of 15 μm was utilized.
Utilizing the natural transparency of zebrafish embryos, we have developed a novel technique to observe chromosome dynamics within a single cell during mitosis in a live vertebrate embryo.
It forms a single cell body layer.
This is a single cell to another cell.
Each dot represents a single cell.
A single cell can grow 15,000 connections with its neighbors.
To select a single cell, click it.
GARP utilizes a single point per grid cell to identify it as present for B. anthracis.
In the course of locating and characterizing the biosynthetic gene cluster for the anticancer natural product apratoxin A (1), we utilized new, single cell methodologies and a novel strategy to overcome some inherent problems with current approaches.
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