After utilizing a library of scaffolding proteins, the strain BLΔpgiΔppc-p168-759 reached the highest titer of -catechin of 910.9±61.3 mg/L from 1.0 g/L of eriodictyol in batch culture with M9 minimal media.
For this purpose, we utilized a library of small-molecular kinase inhibitors.
In this report, we have utilized a library of 130 individual proteinogenic and unnatural amino acid fluorogenic substrates to determine the aminopeptidase specificity of this enzyme.
As the 19S regulatory complex components are essential for viability in yeast, we utilized a library of hypomorphic (DAmP) alleles for essential yeast genes.
Utilizing a library of histone H3 and H4 mutants [ 22], we have identified a number of individual histone residues, many of which are known to be post-translationally modified, that are functionally linked to TORC1 signaling.
In particular, Gibbs and co-workers utilized a library of 41 peptides with CaaL sequences and found that FTase efficiently processed a number of peptides having leucine at X position.
Reviewer #1: The manuscript entitled "The oncogenic protein kinase MELK is essential for mitotic progression in basal-like breast cancer cells" begins with a functional overexpression screen utilizing a library of open reading frames encoding human kinases.
They utilized a library of 1120 compounds, 90% of which have been clinically approved, to screen human endometrial carcinoma cells 59 (Hecellscells which are deficient in MutS homologue-2 (MSH2), one other component of the DNA mismatch repair pathway (MMR).
This high-throughput method was utilized to screen a library of 3,228 compounds represented by 1,948 bioactive compounds and 1,280 small molecules derived via diversity-oriented synthesis.
FACT utilizes a comprehensive library of geometric shapes that represent regions were constraints may be placed for synthesizing flexure systems that possess designer-specified degrees of freedom (DOFs).
