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We utilized the rat model of intrauterine protein deprivation (IUPD) followed up by the long term administration of high salt diet as described previously [ 2, 10, 11].
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Potschka et al utilized the rat kindling model of epileptogenesis to characterize the genomic changes using MPSS.
The in vivo model utilized the rat cerebral vasculatures as a paramagnetic agent compartment, and intravascular agents (Gd-DTPA 30 BSA Gd-DTPA 30 BSAated into the compartment via bolus injections.
Therefore, we have utilized the aging rat model, the emphysematous hamster model and the rat CHF model to determine if activation of the CRF2R will maintain skeletal muscle mass and force production in chronically ill and aged animals.
The intestinal absorption of furosemide was evaluated in the presence and absence of verapamil utilizing the rat intestinal sac model in an experimental study conducted by Al-Mohizea [ 82].
The effects of ospemifene on vaginal weight and epithelial height were examined in three studies utilizing the ovariectomized rat model of menopause.
Utilizing the Sprague Dawley rat model, researchers showed that EGCG reduced tumor burden and number of invasive tumors, and drastically increased the mean latency to the initial tumor in mammary tumor bearing rats [ 21].
In studies utilizing the rat carotid balloon injury model, transfection of a dominant negative JNK prior to injury prevented neointimal formation and markedly suppressed SMC proliferation in both the intima and the media after rat carotid artery injury[ 32].
We utilized the U87 cells, a highly aggressive astrocytoma line, as controls showing that tumors can form in the rat model.
The rat model of silicosis was established.
Using the rat model, the present study demonstrates some limitations.
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