We also describe a number of real clinical trials where biomarker-based designs have been utilized, including a discussion of their respective advantages and challenges.
An explanatory sequential design of a mixed-methods evaluation approach was utilized, including a pre-post menu analysis comparing parent-prepared meals to the catered meals, and stakeholder interviews to determine benefits and barriers.
The exercise intensity ranged from 50to97%7% VO2max, with numerous modes of PA being utilized, including a cycle ergometer, resistance training, walking or running, over a period of 22 days up to 6 months.
To maximize response rate, a modification of Dillman's tailored design method was utilized, including a reminder letter and second mailing of surveys to respondents [ 51].
The hydrologic framework utilized includes a rainfall generator of likely scenarios and a series of hydrologic models that estimate the groundwater recharge and the change in groundwater storage.
Reasons that HTS trafficking screens are not more often utilized include a lack of reagent universality, expensive imaging equipment, and confounding background fluorescence that in many instances requires sophisticated de-convolution algorithms to identify subpopulations of membrane proteins.
The inclusion-specific antibodies utilized include AT8 (1∶1000, Pierce, 24 hour incubation at 4C, mouse) for neurofibrillary tangles and Alpha-synuclein (1∶7500, Zymed, mouse) for Lewy bodies.
To synthesize Co nanoparticles with a controlled size and size distribution, various techniques have been utilized, including evaporation in an inert gas [5], chemical vapor condensation by either heating or laser-irradiating Co2 CO 8 precursor [6, 7], and solution phase reduction of CoCl2 in stabilizing agents [8].
After a period of 6 min of resting state acquisition, a block design was utilized, including three blocks of a 1-min control-task, 1-min stress-task and 1-min rest after task.
A variety of analytical techniques was utilized, including x-ray fluorescence, electron probe, petrography, and reflected light microscopy.
Since then, a variety of computational methods have been utilized, including peak-property-based methods [11,12], machine learning methods [13 16], and spectra-decomposition-based methods [17 19].
