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Moreover, it has been utilized in the setting of the packers, plug equipment, and perforation procedures.
As such, although experimental models indicate that rapamycin has more tolerance-induction properties relative to cyclosporine therapy [40], [41], [42], our data indicate that calcineurin inhibitor therapy may be preferentially utilized in the setting of polarized Th2.R cell therapy for solid organ allografting.
It has since been most commonly utilized in the setting of pancreatic cancer [ 24, 25].
10 These approaches have been utilized in the setting of prenatal diagnosis in at-risk couples.
23, 34, 38 Selective ER downregulators, which have a mechanism of action distinct from that of AIs and tamoxifen, are being utilized in the setting of endocrine-resistant breast cancer, 44– 46 with data available for patients with visceral disease.
Although DL appears safe and the device is approved by the US Food and Drug Administration, DL is still best utilized in the setting of clinical trials designed to resolve issues of sensitivity, specificity, and localization.
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Two experimental settings were utilized: In the first setting, Brn3a promoted anchorage-independent growth of non-malignant cells and accelerated tumour growth of tumourigenic cells, demonstrating a general tumour-promoting role of Brn3a.
This approach is also being utilized in the outpatient setting [15 17].
Our derivation is based on extending the constrained maximum likelihood density based approach that is utilized in the univariate setting as an alternative strategy to the approach originally developed by Kaplan and Meier (1958).
Our derivation is based on extending the constrained maximum likelihood density based approach (Satten and Datta 2001; Zhou 2005) that is utilized in the univariate setting as an alternative strategy to the classical discrete nonparametric hazard function approach (Kaplan and Meier 1958).
29 Other chemotherapeutic agents utilized in the salvage setting include nitrosoureas, etoposide, cyclophosphamide, and platinum compounds.
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