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Finally, we show that RhoA mutations themselves can be utilized in genetic screens.
This striking phenotype has been utilized in genetic screens designed to identify new integrin interacting genes.
Family data utilized in genetic association studies of rare diseases are usually ascertained by initially recruiting individuals with the phenotype of interest from some background population.
When B-LCLs are utilized in genetic research, such aberrations need to be taken into account.
B6 double-congenic mice (homozygous for both mutations) were utilized in genetic epistasis experiments and compared with D2 with respect to clinical indices of iris disease, IOP elevation, and optic nerve damage.
However, whilst these populations can be utilized in genetic and genomic studies, they are not adequate for further analysis such as fine mapping and characterization of target QTLs [ 29].
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Scientists now have another model to utilize in genetic research.
However, the utility of this method can be utilized in other genetic association contexts.
This is unlike the situation in humans where several millions of SNPs are known and being utilized in population genetic analysis [11] and medical diagnostics [12].
Although 120 EST-SSRs have previously been developed from 3,428 EST sequences and utilized in sesame genetic diversity analysis and mapping [ 8, 10, 22], polymorphic markers are few, and marker-assisted gene mapping for important sesame traits or biological processes such as disease resistance, sesame growth and development, and seed formation has thus not been widely implemented.
The objective functions for Nu/Nus and f/fs are constructed using RSM and utilized in multi-objective genetic algorithm to obtain the Pareto-optimal fronts.
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