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The case-crossover design was utilized for our study.
Figure 2 illustrates a typical respiration tracing utilized for our study with the following sequence of injections given in the RP to establish the respiratory capacities with electron flow through both CI and CII separately as well as convergent electron input via the Q-junction (CI + II).
Finally, a case-control study was utilized for our study, and so a conditional logistic regression analysis, conditioned on the matching factors (i.e., gender, age, and smoking status), was performed in order to evaluate the association between the combination of amino acids obtained above and NSCLC.
All procedures on DO mice were approved by the Animal Care and Use Committee at JAX. Breeder pairs of each of the eight DO founder strains were obtained from JAX, housed at the University of Wisconsin Madisonn, WI), and used to generate male pups that were utilized for our study.
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A number of studies from our lab and others have now shown that murine TDP-43 is reduced in response to the overexpression of exogenous TDP-43; one study reported on a conditional TDP-43 model similar to that utilized for our current study [ 19].
NR6WT mouse fibroblasts engineered to express human EGFR were utilized for our baseline modeling studies.
It must be noted that primers utilized for our gene expression studies were designed specifically for detection of human gene sequences.
It should be stressed at this point, that the phenotype we utilized for our genetic association studies with humans was also the quantitative measure of alcohol intake.
The established Arabidopsis promoter database [ 50, 53] and a rice database with 11,370 promoters, prepared in this study, were utilized for our analysis.
For our study we utilized the observations from the most recent measurements, which were made in 2000 and in 2013.
For our study, we utilize the NER model trained on the Genia corpus [ 18].
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