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Emulsion-based delivery systems are widely utilized for encapsulation of hydrophobic bioactive compounds.
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The aqueous core can be utilized for the encapsulation of therapeutic hydrophilic molecules and the membrane can amalgamate hydrophobic drugs within its hydrophobic part [115, 116, 117].
Several techniques (e.g. spray drying, solvent evaporation, microwave irradiation) have been utilized for the encapsulation of active pharmaceutical ingredients (APIs) into inorganic porous matrices.
The ERL- and AS-encapsulated nanoliposomes were utilized for DOX encapsulation into inner compartment of the nanoliposomes using AS-gradient method.
When higher concentration of alginate was utilized for cell encapsulation, the metabolic and angiogenic activity of the cells frozen in the absence of cryoprotectants was comparable to that observed in the presence of DMSO or trehalose.
To investigate effects of DOX-loading methods on EE of DOX in ERL-and DOX-encapsulated nanoliposomes, active loading method such as pH-gradient or AS-gradient method was utilized for DOX encapsulation into the liposomes.
Gelatin is frequently utilized for molecular encapsulation purposes.
The use of nanomaterials with hollow structures for encapsulation of signaling elements is another attractive strategy for ultrasensitive biosensing.
Interestingly, over 3 orders of magnitude in LAP concentration range, the thiol ene reaction can be utilized to form hydrogels with lower irradiation doses than that required to form similar PEG diacrylate networks, suggesting the thiol ene polymerization may be advantageous for encapsulation of proteins or cells with known radical susceptibility.
Those results indicated that the silica encapsulation by microemulsion was suitable for encapsulation of hydrophilic chromophores and was consistent with the literature [15, 51 54].
Another approach for encapsulation of hydrophobic compounds is a swelling and deswelling method [4, 9].
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