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We note that each study utilized distinct methodologies from our work: Goswami et al profiled Trpv1-Cre/TdTomato+ neurons compared to Trpv1-diptheria toxin depleted whole DRG tissue (Goswami et al., 2014).
We note that each of these studies utilized distinct methodologies: two performed analysis of one neuronal population each (Goswani et al, 2014; Thakur et al, 2014 ), and one performed single cell RNA-seq but not population analysis (Usokin et al, 2014).
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Remarkably, it was found that they utilize distinct cultured cell lines for in vitro virus propagation, since PEDV could not be replicated in swine testis (ST) cells expressing native porcine APN (pAPN), which are highly susceptible to TGEV.
Collectively, these findings suggest that different tissues utilize distinct strain-attenuating mechanisms according to their unique structure and cellular phenotype, and these differences likely alter the local biologic response of such tissues and constructs in response to mechanical perturbation.
To address the application speed issue, the USPTO has developed two processes that permit significantly faster examination but utilize distinct rules and additional fees.
These DLBCL subgroups arise from different stages of normal B-cell differentiation, utilize distinct oncogenic mechanisms, and differ in their ability to be cured by chemotherapy.
These findings demonstrate that GPCRs can utilize distinct endocytic pathways, distinguishable by dynamin and beta-arrestin, and that beta-arrestins function as adaptor proteins specifically targeting GPCRs for dynamin-dependent endocytosis via clathrin-coated vesicles.
Moreover, the direct sequence spread spectrum (DSSS) technique, an approach used for enabling multiple users to transmit simultaneously on the same frequency range by utilizing distinct PN [18], is used to encode the node IDs along the packet path into the provenance.
The role of tamoxifen in endometrial carcinogenesis may utilize distinct genomic activity [30].
As such, there is very little overlap between the DH domain binding surfaces of the SH3 domain from Asef and SH3(E) from intersectin-1L, suggesting that these GEFs utilize distinct mechanisms of autoinhibition.
It appears that malignancies arising from different cell types utilize distinct strategies to survive and progress.
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