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In this report, we utilized a yeast model to decipher the cytotoxic action of binaphthoquinones.
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For this purpose, we utilized a yeast-based assay in which we expressed full-length Bak, Bax and VAR F1L.
This novel interaction was identified utilizing a yeast two-hybrid screen [1] and confirmed by coimmunoprecipitation and mass spectrometry analysis.
Utilizing the yeast model system to isolate one of the variables, allows an investigation of the cellular response specific to microgravity conditions.
To describe hospital mortality, we utilized a competing risks model.
To delineate the impact of PD mutations in the haploid state toward mitochondrial function, we utilized yeast as a model system to generate analogous mutations in Ssc1 protein.
We utilized a Δ hsp104 yeast strain to avoid expression of endogenous Hsp104WT.
The authors utilized a previously described cadaver model [ 22].
We present a new yeast model that represents a comprehensive up-to-date collection of knowledge on yeast metabolism.
Based on these findings we utilized a genetic screen in yeast, which uncovered a novel component of the E4orf4 cell death-inducing network, called Ynd1.
As the 19S regulatory complex components are essential for viability in yeast, we utilized a library of hypomorphic (DAmP) alleles for essential yeast genes.
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