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Since we intentionally utilized a tumor model that forms tumors in approximately three weeks, and pregnancy, lactation, and involution are all naturally approximately 21 days (three weeks) in the mouse [ 28], one is able to compare the effects of the developmental stages to tumorigenesis.
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The aim of this study was to examine the effects of the crude extract of Acanthus ebracteatus Vahl (AE) on tumor growth and angiogenesis by utilizing a tumor model in which nude mice were implanted with cervical cancer cells containing human papillomavirus 16 DNA (HPV-16 DNA).
The refolded proteins were utilized in animal tumor model.
To further study the role of IL-25 in breast cancer development, we utilized a mouse model of spontaneous breast tumor - the MMTV-PyMT transgenic mouse.
In the absence of an animal model for human AK disease, studies have utilized mouse tumor models of skin cancer and several tumor cell lines.
Other investigators utilized solid tumor models which sometimes assessed pneumoperitoneum conditions not comparable to the human situation; the great majority of these studies also suggested that the CO2 pnemoperitoneum was a large risk factor.
Three elegant studies elucidated a microRNA network, which regulates RNA-RNA interactions in oncogenic pathways controlling GBM. - While one of the studies utilized a melanoma model, all three studies concentrated on an established GBM tumor suppressor, PTEN.
To understand the role of Met in tumor development and progression, we have utilized a unique mouse model that allows us to compare four different mutations knocked into the Met genomic locus [19].
To describe hospital mortality, we utilized a competing risks model.
In the current study, we utilized a model of WHO Grade II glioma, specifically oligodendroglioma, a clinical stage at which it is often difficult to distinguish tumors from normal brain tissues during surgery.
The vast majority of AuNR-based photothermal ablation studies utilize subcutaneous tumor models established in the flank.
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