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To bypass these inherent complications, we utilized a previously published technique where fusion of the extracellular sequence of the human T-cell antigen CD8α to the cytoplasmic domain of receptor tyrosine kinases leads to constitutively active receptor kinases that can act as oncogenes [ 23- 25].
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Here, we utilize a previously published model [C. Creutz, B.S. Brunschwig, N. Sutin, J. Phys. Chem. B 109 (2005) 10251] to predict IFCTA spectra of metal molecule assemblies and compare the literature observations to these predictions.
We modelled the recorded currents utilizing a previously published kinetic model of the transport cycle of SERT.
In this study, we utilize a previously published polar bear reference assembly that is based on a male sequenced at high coverage (Li et al. 2011), and available short sequence reads from additional male and female polar bears (Miller et al. 2012).
We utilized samples collected from a previously published study [ 4].
We determined Kd values for PCB metabolites and T4 utilizing a modified version of a previously published procedure (Cheng et al. 1977).
23 Outcomes data from a previously published study were utilized in the analysis.15 A decision tree model was utilized to determine the net benefit of therapy over a 12-month time period.
Overall performance results are competitive with those of a previously published study utilizing a sequence-based strategy, while our structure- and sequence-based models provide orthogonal and complementary prediction methodologies, respectively.
Importantly, a previously published study which utilized DAS28 found a significant correlation between ΔDAS28 and ΔCD3 in the synovium of patients with PsA after adalimumab treatment [ 12].
However, we assume that the current interpretation was more accurate than that of a previously published study from 2009, which utilized threefold thicker slices, but also more challenging, due to the younger median age of our patient group [ 20].
The improved performance of IBMT has been demonstrated in a previously published paper [ 52], by utilizing simulated data, 'spike-in' Affymetric datasets, and experimental data.
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