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To further study the role of IL-25 in breast cancer development, we utilized a mouse model of spontaneous breast tumor - the MMTV-PyMT transgenic mouse.
To investigate the protective efficacy of these AdHA vaccine candidates against challenge with the H1N1 virus we utilized a mouse model [17].
For these experiments, we utilized a mouse mammary cancer cell line, EMT6, in which we found robust expression of the endogenous Atf3 gene in preliminary experiments.
To further examine mTOR signaling in Aβ-related synaptic dysfunction, we next utilized a mouse model in which the gene encoding FK506-binding protein 12 (FKBP12) is conditionally deleted in hippocampus and forebrain [29].
To explore this possibility, we utilized a mouse model of diabetic nephropathy (uninephrectomy and streptozotocin (STZ) treatment) to examine the effect of siRNA-induced Gremlin inhibition in vivo on the progression of renal pathology.
As we have shown that PSMs may contribute to whole blood and neutrophil killing of GAS, we sought to determine if PSMs present in a wound could have a similar protective effect against bacteria, we utilized a mouse wound model.
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However, we did not observe this phenomenon in our experiments utilizing a mouse myoblast line and our nanotopography-based platform.
For this reason, we decided to utilize a mouse cell line for our studies and to prepare mutations in ank in the context of the mouse cDNA sequence.
Utilizing a mouse model, the authors found that topical cyclosporine might represent an effective drug for the management of patients with nasal polyps.
In conclusion, we have investigated the imatinib and everolimus combination effect against human Ph+ quiescent leukemic cells utilizing a mouse model.
Serum TSH was measured by a chemiluminescence immunometric assay utilizing a mouse monoclonal antibody to TSH immobilized on a polystyrene bead and a goat polyclonal antibody to TSH conjugated with an acridinium ester.
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